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Temocillin disodium

CAS No. 61545-06-0

Temocillin disodium( —— )

Catalog No. M35223 CAS No. 61545-06-0

Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Temocillin disodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity that can be used to study urinary tract infections, bloodstream infections, pneumonia, intra-abdominal infections, central nervous system infections, skin and soft tissue infections, surgical site infections and bone and joint infections.
  • Description
    Temocillin disodium, a 6-α-methoxy penicillin, possesses antibacterial activity.
  • In Vitro
    ——
  • In Vivo
    Temocillin dosing regimens of 200 mg/kg every 4 and 6 h remained significantly effective in reducing bacterial titres in kidneys against the two strains, with no significant difference between the parental strain and its transconjugant.
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    61545-06-0
  • Formula Weight
    458.42
  • Molecular Formula
    C16H16N2Na2O7S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 250 mg/mL (545.35 mM; Ultrasonic)
  • SMILES
    CO[C@@]1(NC(=O)C(C(=O)[O-])c2ccsc2)C(=O)N2[C@@H](C(=O)[O-])C(C)(C)S[C@@H]21.[Na+].[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. K Jules, et al. Antibacterial activity and beta-lactamase stability of temocillin. Antimicrob Agents Chemother. 1982 Sep;22(3):453-60.?
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